Asymmetric “Janus” Biogel for Human‐Machine Interfaces

Human-machine interfaces (HMIs) are essential for effective communication between machines and tissues. However, mechanical biological mismatches, along with weak adhesion rigid electronic devices soft tissue, often cause unreliable responses affect the signal recording of HMIs. In this study, an asymmetrical “Janus” biogel patch one side firmly adhering to tissues, other surface having little minimal interactions surrounding environments has been developed. A series analytical, mechanical, electrical tests performed investigate as a functional biocompatible HMI. It is found that gallic acid-modified gelatin adhesive on exhibits body temperature-dependent tissue adhesion, enabling low modulus seamless skin contact. The tough gelatin/glycerol gel layer, which thermally welded into layer functions encapsulant prevent external interference due adhesion. encapsulation also friction coefficient when wet proves be reliable alternative barrier conventional materials. scientific insights engineering principles revealed in type will applicable broad range biomedical applications, such epidermal electrodes or skin-adhesive wearable devices.